Proteins Lennart Voß Marie Ullrich. 1. Central questions What are proteins? How does the human body produce proteins? Which functions do proteins fulfill?

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Proteins Lennart Voß Marie Ullrich

1. Central questions What are proteins? How does the human body produce proteins? Which functions do proteins fulfill?

2. Amino acids Hydrocarbon with acid and amino group Linked by peptide bonds Proteins are built out of at least 100 amino acids

3. Structure Primary structure Secondary structure Tertiary structure Quaternary structure

3. Structure 0Helices.JPGhttp://cmgm.stanford.edu/biochem201/Slides/Protein%20Structure/Alpha%2 0Helices.JPG, date of access:

3. Structure neu/aminosaeuren/sek_b1.htmlhttp://www2.chemie.uni-erlangen.de/projects/vsc/chemie-mediziner- neu/aminosaeuren/sek_b1.html, © Prof. Dr. J. Gasteiger, Dr. A. Schunk, CCC Univ. Erlangen, Mon Nov 26 17:05: GMT, date of access:

4. Protein biosynthesis Transkription = m-RNA is built as a copy of a DNA section Translation = t-RNA connects to m-RNA, amino acids on t-RNA get connected and built a protein

5. Enzymes Catalyze chemical reactions Work by lock and key model

6. Membrane proteins Some small molecules can diffuse through membranes Bigger molecules need to be transported by membrane proteins

7. Further functions Structure proteins e.g. collagen Animal toxins Hormones e.g. insulin

8. Summary Proteins… Are built out of a lot of amino acids form extremely complex structures fulfill a lot of different and important functions in human bodys

9. References Dr. W. Baltes, Lebensmittelchemie, Springer- Verlag, 1. Auflage, S Prof. Dr. W. Probst, P. Schuchardt Biologie – Basiswissen Schule, Duden Schulbuchverlag, 2. Auflage, S P. Karlson, Kurzes Lehrbuch der Biochemie, Georg Thieme Verlag, 11. Auflage, S C. A. Schlieper, Grundfragen der Ernährung, Dr. Felix Büchner – Verlag Handwerk und Technik, 7. Auflage, S.79-86