Biotechnology in Germany From BioRegions to BioClusters Keys for succes Dr. Klaus Plate CEO Heidelberg Technology Park Sino-European Forum on Innovation Clusters Paris, January 25, 2007

Biotechnology in Europe 50 100 150 200 250 300 Ireland Spain Norway others Italy Denmark Belgium Finland Netherlands Switzerland Sweden France UK Germany number of companies big (150 and more employees) medium (50 to 149 employees) small (1 to 49 employees) Start-Up (up to 2 years) Source: Ernst & Young

German BioRegions Bioinitiative Nord (Hamburg- Kiel-Lübeck BioRegio Greifswald-Rostock Region Bremen Region Nordwestl. Nieder- sachsen BioTOP Berlin-Bran- denburg BioRegio N Braunschweig- Hannover- Göttingen) BioRegio Rheinland (Köln-Bonn- Aachen BioMIT Mittelhessen (Marburg- Gießen) BioRegion Halle-Leipzig BioRegio Jena BioRegion Rhein-Main (Frankfurt-Mainz) BioRegion Rhein-Neckar- Dreieck BioRegio Regensburg BioRegio Stuttgart/ Neckar-Alb (Tübingen) Biotech- nologie Ulm Biotech- nologie München BioRegio Freiburg

German BioRegions Bioinitiative Nord (Hamburg- Kiel-Lübeck BioRegio Greifswald-Rostock Region Bremen Region Nordwestl. Nieder- sachsen BioTOP Berlin-Bran- denburg BioRegio N Braunschweig- Hannover- Göttingen) BioRegio Rheinland (Köln-Bonn- Aachen BioMIT Mittelhessen (Marburg- Gießen) BioRegion Halle-Leipzig BioRegio Jena BioRegion Rhein-Main (Frankfurt-Mainz) BioRegion Rhein-Neckar- Dreieck BioRegio Regensburg BioRegio Stuttgart/ Neckar-Alb (Tübingen) Biotech- nologie Ulm Biotech- nologie München BioRegio Freiburg

20 million DM for the special region: BioRegio Funding 50 million DM for research projects in biotechnology for three model regions: BioRegio Rhineland (Köln, Bonn, Achen) BioRegion Rhine-Neckar-Triangle (Heidelberg) Biotechnology Munich (München) plus 20 million DM for the special region: BioRegio Jena Source: BioRegion Rhine-Neckar-Triangle

Conditions for BioRegio Funding The perspective of a short or medium-term commercialisation of the results, preferentially by founding a biotech company The commercial realization of the results within the region The confinancing of the project by private capital, generally with at least 50 % of the total cost of the project Time span: 1st Jan 1997 – 31st Dec 2001 Source: BioRegion Rhine-Neckar-Triangle

Selecting projects for BioRegio Funding I. Criteria Scientific Quality Competitiveness (patent situation) Creation of Jobs Focus on regional strength Source: BioRegion Rhine-Neckar-Triangle

Since the launch of the BioRegio Contest in 1997: 55 new biotech companies in the Heidelberg BioCluster 45 research-driven companies in molecular biotechnology 1.800 jobs created directly in biotech companies 1.500 jobs in research-driven biotech companies 8.000 jobs in the industry and 6.000 jobs in research institutions are dependent on biotechnology Source: BioRegion Rhine-Neckar-Triangle

German BioClusters Bioinitiative Nord (Hamburg- Kiel-Lübeck BioRegio Greifswald-Rostock Region Bremen Region Nordwestl. Nieder- sachsen BioTOP Berlin-Bran- denburg BioRegio N Braunschweig- Hannover- Göttingen) BioRegio Rheinland (Köln-Bonn- Aachen BioMIT Mittelhessen (Marburg- Gießen) BioRegion Halle-Leipzig BioRegio Jena BioRegion Rhein-Main (Frankfurt-Mainz) BioRegion Rhein-Neckar- Dreieck BioRegio Regensburg BioRegio Stuttgart/ Neckar-Alb (Tübingen) Biotech- nologie Ulm Biotech- nologie München BioRegio Freiburg

BioClusters Keys for success

BioClusters Science Base Universities Research Institutes

BioClusters Company Base Big Companies Medium-sized companies Start-ups

BioClusters Financial Base Availability of „smart“ equity and debt-finance Seed money Venture money

BioClusters Human Resources Availability of skilled workforce Scientists Business Professionals Technicians Post-docs

BioClusters Additional critical factos for success Easy to reach by air, car, railway Quality of life

The drivers of BioClusters BioParks The drivers of BioClusters The right environment to start and grow biotech companies

Heidelberg BioCluster BioClusters The Heidelberg Technology Park is a BioPark Center of the Heidelberg BioCluster

Heidelberg BioCluster Heidelberg Technology Park Profile 500.000 sqft lab and office space 75 tenant companies 1.300 employees, 1.500 expected 200 Associated Members

Heidelberg BioCluster Heidelberg Technology Park The Heidelberg Technology Park is an international Life Science Park, Center of the Heidelberg BioCluster. The Park is closely related to the Heidelberg University and to the worldfamous research institutes located here.

Heidelberg BioCluster Heidelberg Technology Park Technology Park Services Helping with renting office and lab space financing managment marketing legal affairs

Heidelberg BioCluster Heidelberg Technology Park Technology Park Services (examples) conference service seminars, workshops market place for machines, lab material, services, jobs online and print platforms to communicate organizing meetings conference center restaurant Kindergarten parking

Heidelberg BioCluster Heidelberg Technology Park Technology Park Networking Regional, national, international developing a regional BiotechCommunity working with national and international associations creating strategic alliances and partnerships

22 Partners in America, Asia, Europe Heidelberg BioCluster Heidelberg Technology Park TP Sisterpark Network Sisterpark Network 22 Partners in America, Asia, Europe A worldwide alliance to explore international markets and to offer information, collaboration and partnering.

Heidelberg Technology Park Sisterpark Network

Heidelberg BioCluster Heidelberg Technology Park CEBR: Council of European BioRegions  Uppsala  Tallinn Cambridge Oxford   Flanders  Berlin  Heidelberg Paris   Munich Lyon  Basel  Barcelona

Council of European BioRegions CEBR 'Building a competitive European biotechnology sector on the world stage’ 1

CEBR – the need ….an observation on European biotech Hundreds of small companies across Europe • A need to work together for best result in competitive world market • Diverse sources of assistance – not always apparent/easily accessible Founded on excellent science but must operate effectively to succeed 'Building a competitive European biotechnology sector on the world stage’ 1

CEBR – the history Small group with common interest: Improving practical support for their biocommunities Creating network with appropriate/best point of contact in every biocommunity Promoting European biotechnology Network outline developed Funding achieved 'Building a competitive European biotechnology sector on the world stage’ 1

CEBR – what it can offer • Operational support – companies should succeed on science, not fail on business practice • Europe-wide biotechnology network – rapid access to biotechs • Promotion of European biotechnology on world stage • Signposts to what works well 'Building a competitive European biotechnology sector on the world stage’ 1

CEBR – what it does …. The ‘golden rules’ • ‘Bottom up’ – driven by biotech’s practical needs • Activities with direct benefit to biotechs • Working network – proactive members • Co-operation: co-operate to compete 'Building a competitive European biotechnology sector on the world stage’ 1

TP Contact Heidelberg BioCluster Heidelberg Technology Park Contact: Dr. Klaus Plate, CEO Technologiepark Heidelberg GmbH Marktplatz 10, 69117 Heidelberg, Germany Phone: +49 6221 58-20500 Fax: +49 6221 58-20990 E-mail: klaus.plate@heidelberg.de technologiepark@heidelberg.de Web: www.technologiepark-heidelberg.de

Thank you for your attention.